(S)-ABT 102( —— )

Catalog No. M34487 CAS No. 808756-70-9

N-[(1S)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea is a potent TRPV1 antagonist, blocking activation of TRPV1 by capsaicin with the IC50 of 123 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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5MG	255	Get Quote
10MG	374	Get Quote
25MG	545	Get Quote
50MG	762	Get Quote
100MG	1017	Get Quote
500MG	2034	Get Quote
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Biological Information

Product Name

(S)-ABT 102
Note

Research use only, not for human use.
Brief Description

N-[(1S)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea is a potent TRPV1 antagonist, blocking activation of TRPV1 by capsaicin with the IC50 of 123 nM.
Description

(S)-ABT-102 is a TRPV1 Antagonist, with an IC50 of 123 nM. (S)-ABT-102 has analgesic activity.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

TRP/TRPV Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

808756-70-9
Formula Weight

348.44
Molecular Formula

C21H24N4O
Purity

>98% (HPLC)
Solubility

——
SMILES

N(C(NC1=C2C(NN=C2)=CC=C1)=O)[C@@H]3C=4C(=CC(C(C)(C)C)=CC4)CC3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Gomtsyan A, et al. Identification of (R)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)urea (ABT-102) as a potent TRPV1 antagonist for pain management. J Med Chem. 2008 Feb 14;51(3):392-5.?

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